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An analogous attenuation was pointed out in nNOS knockout mice and with naltrexone (opioid antagonist) administration [29, 31]. Whilst the two neuropathic and abdominal/inflammatory types of pain exhibit the release of endogenous opioids to be a therapeutic mechanism, the professional- or antinociceptive purpose of NOS and RNS continues to be contr

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The same attenuation was observed in nNOS knockout mice and with naltrexone (opioid antagonist) administration [29, 31]. Although both equally neuropathic and abdominal/inflammatory models of pain exhibit the discharge of endogenous opioids for a therapeutic mechanism, the pro- or antinociceptive function of NOS and RNS continues to be controversia

read more